Lymphovascular Abnormalities Under Tattoos

Haute Ecole Bruxelles-Brabant19 enrolled

Overview

The number of tattooed people is increasing and some complications secondary to tattoos suggest that the lymphatic vascular system might be implicated in their pathogenesis. Abnormalities have been described at the level of the lymph nodes draining the tattooed areas but nothing was reported about the lymphatic vessels under tattoos. This is the aim of the present work.

19 subjects with 20 tattooed skin surfaces were enrolled after written informed consent and the lymphvascular drainage under the tattooed surface was studied using one near infrared camera device after one intradermal injection of Indocyanine Green.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Tattoo

Interventions

near infra red fluorescence lymphatic imagingDIAGNOSTIC_TEST

ICG (0.2 ml from 25mg of ICG diluted by 5.0 ml of aqua ad injectabilia) was injected intradermally at the basis of the tattooed cutaneous area and at one point chosen so that the tracer had to flow under this area directly towards the root of the limb

Eligibility

Sex: ALLMin age: 18 YearsMax age: 40 Years

Medical Language ↔ Plain English

Inclusion Criteria: * presence of one tattoo at the level of one limb * written informed consent Exclusion Criteria: 1. History of iodine allergy or anaphylactic reactions to insect bites or medication; 2. Hyperthyroidism; 3. Severe cardiac or pulmonary disease; 4. Significant renal failure (creatinine \> 400 μmol/l); 5. Pregnancy; 6. any known disease of the skin (such as psoriasis); 7. any disease known to affect the cutaneous tissues (such as diabetes); 8. any previous operation and/or trauma at the level of tattooed limb; 9. familial history of lower limb edemas: 10. skin infection after the tattoo

Locations (1)

Pierre Bourgeois

Paliseul, Belgium

Outcomes

Primary Outcomes

normal or abnormal lympho-vascular drainage

The following pictures were considered as normal \- lymphatic vessels are well seen and drainage is fast spontaneously

Time frame: imagings were performed directly after the injection (duration 3 minutes)

normal or abnormal lympho-vascular drainage

The following pictures were considered as normal \- lymphatic vessels are well seen after stretching and massages of the injected site

Time frame: imagings were performed directly after the stretching and massages (duration 3 minutes)

normal or abnormal lympho-vascular drainage

The following pictures were considered as normal \- lymphatic vessels are well seen after 30 minutes of normal activities and direct between the injected site and-towards the first lymph node at the root of the limb

Time frame: imagings were performed after a period of normal activities (duration 30 minutes)

Data from ClinicalTrials.gov

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