The induction dose of rocuronium is typically decided based on the patient's body weight, but the effect duration of rocuronium is variable. Some studies suggest that body composition analysis data, such as skeletal muscle mass or total body water, may correlate better with the duration time of rocuronium. Therefore, we plan to analyse body composition in patients undergoing total intravenous general anesthesia, give the patients a fixed dose (50mg) of rocuronium, and check the correlation between duration time of rocuronium and body composition analysis data.
Study Type
OBSERVATIONAL
Enrollment
88
Patients will undergo body composition analysis using bioelectical impedance method before anesthesia.
Samsung Medical Center, Sungkyunkwan University, School of Medicine
Seoul, South Korea
time to TOF1
correlation between the time from induction to recovery of 1st TOF twitch and age, sex, ASA class, body weight, and body composition analysis data
Time frame: up to 1 hour after rocuronium administration during induction of anesthesia
time to TOF4
correlation between the time from induction to recovery of 4th TOF twitch and age, sex, ASA class, body weight, and body composition analysis data
Time frame: up to 1.5 hour after rocuronium administration during induction of anesthesia
time to loss of TOF
correlation between the time from injection of rocuronium to complete loss of TOF twitch and age, sex, ASA class, body weight, and body composition analysis data
Time frame: up to 5 minutes after rocuronium administration during induction of anesthesia
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