Retrospective observational study of all patients undergoing aortic root surgery with aortic valve conservation, using the inclusion technique described by Tirone David, between January 1, 2004 and December 31, 2020, at six centers (Nantes - Rennes - Brest - Angers - Tours \[two centers\]). The main objective of this study is to evaluate the survival without re-intervention for aortic valve dysfunction (surgery or TAVI).
Retrospective observational study of all patients undergoing aortic root surgery with aortic valve conservation, using the inclusion technique described by Tirone David. Inclusion criteria: Patients undergoing aortic root surgery with conservation of the aortic valve, according to the inclusion technique described by Tirone David, between January 1, 2004 and December 31, 2020, at one of the six centers: Nantes, Rennes, Brest, Angers, Tours (two centers). Non-inclusion criteria: Prosthetic replacement of the aortic valve intraoperatively during the first operation. Objectives and endpoints : * The survival without re-intervention for aortic valve dysfunction (surgery or TAVI) * The overall cardiovascular survival * The survival without aortic insufficiency of grade equal to or greater than two * The survival without aortic infective endocarditis * Assessment of long-term stroke risk Assessment of the risk of a major bleeding event in the long term Data analysis : The AORTLANTIC study is included in the EPICARD registry which is the official, national database of the French Society of Cardiac Surgery. Study data will then be collected using EPICARD's electronic Case Report Form (eCRF) and then analyzed using a multivariate Cox model. For the follow-up, the WEPI eCRF is used.
Study Type
OBSERVATIONAL
Enrollment
529
There is no intervention in this retrospective study.
Nantes University Hospital
Nantes, France
Evaluate the survival without re-intervention for aortic valve dysfunction (surgery or TAVI), after aortic root surgery with conservation of the aortic valve, according to the inclusion technique described by Tirone David
Number of patients alive without re-intervention for aortic valve dysfunction (surgery or TAVI)
Time frame: Conditional survival starting at 30 days
Evaluate the overall cardiovascular survival results
Number of patients alive
Time frame: up to 17 months
Evaluate the absence of aortic insufficiency greater than or equal to grade two between the two types of aortic tube graft (right prosthesis or Valsalva prosthesis)
Number of patients alive without aortic insufficiency of grade equal to or greater than two
Time frame: up to 17 months
Evaluate the risk of infective endocarditis
Number of patients alive without aortic infective endocarditis
Time frame: up to 17 months
Evaluate the risk of stroke
Number of patients alive without stroke
Time frame: up to 17 months
Evaluate the risk of major bleeding event
Number of patients alive major bleeding event
Time frame: up to 17 months
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