Randomized Controlled Clinical Investigation Evaluating the Effect of Adipose Tissue Processed With the SyntrFuge™ System in the Healing of Diabetic Foot Ulcers

Inclusion Criteria: 1. Subjects who have Diabetic Foot Ulcer located at the plantar or dorsal aspect of the foot or the heel with a surface area of 1.0cm2 - 25cm2 2. Index ulcer has been present for greater than four weeks 3. Diabetics included will be those with HbA1c ≤ 12% 4. Subjects aged 18 - 85, inclusive 5. The target ulcer has been offloaded for at least 14 days Exclusion Criteria: 1. Subjects without decisional capacity 2. Subjects unable to give informed, written consent 3. Subjects with active infection (redness, swelling, pain, suppuration) 4. Subjects with active osteomyelitis to the index ulcer 5. Subjects with previous treatment with Negative Pressure Wound Therapy, growth factors, radiation, hyperbaric O2, or bioengineered tissue product within 30 days of Screening 6. Subjects with a previous diagnosis of HIV or Hep C 7. Subject is pregnant or breast feeding 8. Subjects receiving oncological treatments ongoing or previous (past 5 years) and/or neoplastic lesions 9. Subjects under corticosteroid therapy, unless taking dose of 5mg/dl or less 10. Subjects with any other condition that, in the opinion of the investigator, makes the subject inappropriate to take part in this study