The Treatment of Magnesium Sulfate and Nifedipine in Preterm Labor Threat

N/AUnknownNCT05520021

Konya Meram State Hospital30 enrolled

Overview

Comparison of the effects of Nifedipine and MgSO4 therapies on maternal and fetal blood flow.

In this study, the investigators aim to compare the effect of Nifedipine and MgSO4 therapies on Doppler parameters of the uterine, umbilical, middle cerebral arteries, and ductus venous in the first 48 hours of therapy in pregnancies with preterm labor threat and also compare perinatal outcomes after delivery between the groups.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

Conditions

Preterm Labor Without Delivery Pregnancy Preterm

Interventions

NifedipineDRUG

A total of 30 pregnancies with preterm labor threats will be treated with Nifedipine.

Magnesium sulfateDRUG

A total of 30 pregnancies with preterm labor threats will be treated with Magnesium sulfate.

Eligibility

Sex: FEMALEMin age: 18 YearsMax age: 38 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * pregnancies with preterm labor threat between 28-34 weeks gestational ages Exclusion Criteria: * Cervical dilatation at \> 4 cm and/or cervical effacement \>80%, * Multiple pregnancies, * Pregnancy complications including preeclampsia, ablatio placenta, intrauterine growth restriction, placenta previa, gestational diabetes

Locations (1)

Hasan Ali Inal

Antalya, Turkey (Türkiye)

RECRUITING

Outcomes

Primary Outcomes

Doppler parameters

Pulsality index of middle cerebral artery.

Time frame: Gestational age at delivery (weeks)

Secondary Outcomes

Perinatal outcomes

NICU admission

Time frame: Gestational age at delivery (weeks)

Central Contacts

Merve Turk

CONTACT

+90 5050 494 20 00 drmerveturk@gmail.com

Data from ClinicalTrials.gov

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