Pilot, single-blind, randomized and controlled study to evaluate the changes produced in the visual function of patients with glaucoma after oral administration for 3 months of citicoline and docosahexaenoic Acid (DHA) vs citicoline and docosahexaenoic Acid (DHA) vs vitamin C.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
SINGLE
Enrollment
73
Every subject randomized into this group have to take 2 sachets of Cebrolux 800 (362 mg of citicoline per day), every day, for 3 months.
Every subject randomized into this group have to take 3 pills of Brudypio 1.5g (1050 mg of DHA per day), every day, for 3 months.
Every subject randomized into this group have to take 2 sachets of Cebrolux 800 and 3 pills of Brudypio 1.5g per day, every day, for 3 months.
Institut Catala de Retina
Barcelona, Spain
Effect on Mean Defect (MD)
Evaluation of changes on the MD (decibels) with study treatment.
Time frame: From Baseline to Month 3.
Effect on Visual Field Index (VFI)
Evaluation of changes on the VFI (%) with study treatment.
Time frame: From Baseline to Month 3.
Evaluation of the changes produced in the intraocular pressure (IOP)
To compare IOP (mmHg) measurements with study treatment.
Time frame: From Baseline to Month 3.
Evaluation of tolerance
Describe the tolerance and the adverse events with study treatment.
Time frame: From Month 1 to Month 3
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Every subject randomized into this group have to take 1 pills of Vitamin C (500 mg per day), every day, for 3 months.