The web-based continuity of care intervention model to provide comprehensive nursing interventions for obese children with NAFLD, always tracking their performance status, enabling them to grasp the knowledge of healthy weight loss, develop good lifestyle habits, and reduce their weight, thus reducing the incidence of NAFLD in children.
The web-based continuity of care intervention model to provide comprehensive nursing interventions for obese children with NAFLD, always tracking their performance status, enabling them to grasp the knowledge of healthy weight loss, develop good lifestyle habits, and reduce their weight, thus reducing the incidence of NAFLD in children.The primary outcome are serum biomarkers such as alanine aminotransferase (ALT) and gamma-glutamyl transferase (GGT) . Second outcomes are: aspartate aminotransferase, and liver imaging (liver ultrasound and magnetic resonance imaging), BMI, waist-to-hip ratio and quality of life. In addition, socio-demographic characteristics such as age, gender and ethnicity will be recorded. All outcomes were measured at baseline, week 4, week 16, week 24, week 36, and week 48 to determine the trajectory of change in outcome variables over intervention process.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
SINGLE
Enrollment
85
1. Establishing management teams. 2. Establishment of a nursing intervention team. 3. Daily uploading of health intervention records 4. Regularly delivering related health knowledge. 5. Home visiting 6. Psychological guidance. The health teachers in the team should closely understand the psychological trends of the patients during the telephone follow-up and home visits and verbally communicate more with the children to stimulate them to develop good living habits and increase their confidence in healing.
Caixia Tian
Shaoxing, Zhejiang, China
The change of alanine aminotransferase（ALT）and gamma-glutamyl transferase（GGT）
The primary outcome are serum biomarkers such as alanine aminotransferase (ALT) and gamma-glutamyl transferase (GGT) .
Time frame: Change from Baseline ALT and GGT at 48 weeks
The change of aspartate aminotransferase
Second outcome is aspartate aminotransferase
Time frame: Change from Baseline aspartate aminotransferase at 48 weeks
The change of liver imaging
Third outcome is liver imaging
Time frame: Change from Baseline liver imaging at 48 weeks
The change of BMI
Fourth outcome is BMI
Time frame: Change from Baseline BMI at 48 weeks
The change of waist-to-hip ratio
Fifth outcome is waist-to-hip ratio
Time frame: Change from Baseline waist-to-hip ratio at 48 weeks
The change of quality of life
Sixth outcome is quality of life
Time frame: Change from Baseline quality of life at 48 weeks
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