To investigate the clinical application of ultrasound-guided continuous low serratus anterior plane block in open surgery for hepatocellular carcinoma.
METHODS: Patients with hepatocellular carcinoma who attended our hospital from January 2021 to April 2023 were divided into CS group and N group according to the random number table method; CS group underwent ultrasound-guided continuous low anterior serratus plane block and N group underwent ultrasound-guided single anterior serratus plane block combined with rectus abdominis sheath block; the operation time, anesthesia time, incision length, sensory block time and sensory block maintenance time were counted and recorded. Pain score (NRS) was used to detect analgesia; alanine aminotransferase (ALT), liver function aspartate aminotransferase (AST), and prothrombin time (The time of thrombin, NRS) were measured by fluorescent quantitative PCR. （The time of thrombin (APTT), total bilirubin (TBIL) levels and adverse reactions.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
DOUBLE
Enrollment
160
Low anterior serratus plane block, move the mid-axillary line 4 and 5 intercostal puncture points are moved down and the puncture is changed to 7 and 8 intercostal.
Ultrasound-guided single anterior saw plane block was performed, and a needle was injected between the 4th and 5th costals in the midaxillary line.
The First People's Hospital of Neijiang
Neijiang, Sichuan, China
RECRUITINGBlock plane
The effect of anesthesia after ultrasound-guided nerve block was measured using planimetry, as well as the area being anesthetized. The chest wall between T2-T9 and ice cotton balls was used to assess the extent and extent of anesthesia block.
Time frame: 30 minute after the surgery begins
visual analogue scale
The visual analogue scale (VAS) of the patient's pain was recorded 24 hours after operation.
Time frame: 24 hours after surgery
visual analogue scale
The visual analogue scale (VAS) of the patient's pain was recorded 48 hours after operation.
Time frame: 48 hours after surgery.
visual analogue scale
The visual analogue scale (VAS) of the patient's pain was recorded 36 hours after operation.
Time frame: 36 hours after surgery.
Patient satisfaction
The patient's satisfaction with the analgesia 2 days after surgery was recorded. The analgesic effect: 1-3 as satisfactory, 4-6 as unsatisfactory, 7-10 as ineffective
Time frame: 48 hours after surgery.
Remedial analgesic drug
Whether other analgesic drugs were added within 24 hours after operation was recorded
Time frame: 24 hours after surgery.
Intraoperative blood pressure changes
Blood pressure changes were measured directly by radial artery puncture and recorded. The changes in blood pressure and heart rate before and after excision and the use of intraoperative opioids.
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Time frame: 2 hours after the beginning of surgery.
Intraoperative heart rate changes
The curve of the change of the operative heart rate was recorded through the anesthesia machine.
Time frame: 2 hours after the beginning of surgery.