Portable Scalp Cooling System for the Improvement of Chemotherapy-Induced Hair Loss in Patients With Metastatic Breast Cancer

Inclusion Criteria: * Documented informed consent of the participant * Age: \>= 18 years * Eastern Cooperative Oncology Group (ECOG) =\< 2 * Ability to read and understand English or Spanish for questionnaires * Documented diagnosis of metastatic breast cancer with at least a 6 month life expectancy * A planned course of taxane based chemotherapy in the metastatic setting, including paclitaxel, docetaxel or abraxane * At least 6 months from the last chemotherapy causing hair loss with complete recovery of hair * Willing to be contacted for brief annual assessments for five years * Women of childbearing potential (WOCBP): negative urine pregnancy test * Agreement by females of childbearing potential to use an effective method of birth control or abstain from heterosexual activity for the course of the study * Childbearing potential defined as not being surgically sterilized (men and women) or have not been free from menses for \> 1 year (women only) Exclusion Criteria: * Autoimmune disease affecting hair; e.g. alopecia areata, systemic lupus with associated hair loss * A history of whole brain radiation with persistent hair thinning or alopecia, or concurrent whole brain radiation therapy * Exposure to other investigational agents, drugs, device or procedure that may cause hair loss * Patients with female pattern baldness resembling picture I-3 or higher on the Savin scale * Any cutaneous scalp metastases * Clinically significant liver dysfunction considered significant as determined by treating physician that would limit the patient's ability to administer the scalp cooling device * Clinically significant renal dysfunction considered significant as determined by treating physician that would limit the patient's ability to administer the scalp cooling device * A history of persistent grade 2 (or higher) alopecia induced by prior chemotherapeutic regimens * Evidence of untreated or poorly controlled hyper or hypothyroidism * American Society of Anesthesiologist Class \>= 3 * Any other condition that would, in the Investigator's judgment, contraindicate the patient's participation in the clinical study due to safety concerns with clinical study procedures * Pregnant or breastfeeding * Prospective participants who, in the opinion of the investigator, may not be able to comply with all study procedures (including compliance issues related to feasibility/logistics)