The Efficacy & Safety of rTMS for Upper-limb Motor Function Recovery in Subcortical and Brainstem Stroke

Inclusion Criteria: * 19-80 years old * Radiologically confirmed ischemic stroke with subcortical and brainstem lesions within 90 days * Fugl-Meyer assessment scale (upper extremity) \> 15 * Mini-mental status exam (the Korean version) \> 14 with appropriate cognitive function * Written informed consent Exclusion Criteria: * Fugl-Meyer assessment scale (wrist) \< 1 or Fugl-Meyer assessment scale (hand) \< 1 * Hemorrhagic stroke or traumatic brain injury * Cerebellar stroke * Previous history of stroke * Traumatic brain injury * Previous history of brain surgery * Need for intensive care due to complications associated with stroke (e.g. pneumonia, infection, hemodynamic instability) * History of psychological or neurological diseases * History of pain or muscular weakness of upper limbs which may interfere with rehabilitation * History of seizure or epilepsy * Aphasia * Skin lesions in the stimulation site of scalp * Intracranial metal implant * Inability to receive regular physical or occupational therapy * Disagreement to use contraception in women of childbearing age