Cast Or ePineural Suture for Digital Nerve Injuries - a Randomised Controlled Study

Karolinska Institutet166 enrolled

Overview

Nerve injury in the fingers is a common injury and affects people of all ages. The treatment usually offered to patients is surgery and various types of rehabilitation. There is a lack of knowledge and research on how these injuries should be treated in the best way and how well sensory function can be restored after an injury. In this research project, we will investigate results after treatment for digital nerve injuries by entailing a randomised controlled trial allocating patients with isolated digital nerve injuries to either surgical repair or non-operative treatment in a cast. Primary outcome is digital nerve function as measured by 2-points discrimination at 1 year after treatment. Secondary outcomes include finger mobility, dexterity, handfunction, occurence of pain and anxiety and time on sick leave.

Patients over the age of 20 with an acute traumatic isolated digital nerve injury to any of the fingers and not in the thumb will be investigated for inclusion in the study. After informed written consent a sealed envelope randomisation will allocate patients to treatment with either surgical exposure and epineural suture or non-operative treatment in a cast. Due to the nature of treatment arms the allocation will not be blinded. Clinical follow-up and investigation of primary and secondary outcomes will be conducted at 3 weeks, 3 months, 6 months and 1 year after inclusion.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

166

Conditions

Digital Nerve Injury

Interventions

Epineural suturePROCEDURE

2 or three sutures

Non-operative treatmentPROCEDURE

The injured finger is protected in a plaster cast

Eligibility

Sex: ALLMin age: 20 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Clinical signs of isolated traumatic digital nerve injury in digits 2, 3, 4 or 5. * Patient age =\> 20 years on day of injury. * Injury location on volar aspect of finger. * Acute sensory dysfunction in suspected digital nerve injury area. Exclusion Criteria: * Digital nerve injury ot the thumb * Digital nerve injury in the palm of the hand (i e proximal to the finger base) * Patient does not speak or read the Swedish language. * Abusive drug or alcohol use * Dementia. * Injury mor than 7 days at dianosis AND/OR operative treatment cannot be offered within 10 days from injury. * Neurologic disease. * Ongoing infektion in the injured finger. * concomittant tendoninjury or fracture in injured or adjacent finger. * Injury mechanism is of blunt or crush charachter

Locations (1)

Karolinska Institutet Södersjukhuset, Department of clinical research and education

Stockholm, Stockholm County, Sweden

RECRUITING

Outcomes

Primary Outcomes

Static two points discrimination (S2PD)

a static two points discrimination test performed by an occupational therapist of the injured finger

Time frame: one year after injury