Ozone Gel Application in Controlled Type 2 Diabetic Patients With Periodontitis

Cairo University24 enrolled

Overview

The adjunctive topical subgingival application ozone gel creates a great improvements in the clinical, bacteriological and immunological parameters over the gold standard of periodontal pocket treatment alone.

The aim of this study is to compare the effect of using ozone gel as a locally delivered adjunct to scaling and root planning versus scaling and root planning alone on the clinical parameters in stageIII grade B in periodontitis patients with controlled diabetic patients.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Periodontal Diseases

Interventions

Ozone gelDRUG

application of Ozone gel after scaling by ultrasonic scaler in the bottom of periodontal pocket

Eligibility

Sex: ALLMin age: 18 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: 1. Patient with controlled diabetic type II. (HgA1C \<7) (Mori et al., 2021) 2. Adult patients above 18 years old. 3. Patients with stage III and grade B periodontitis. 4. Patients accept 3-months follow-up period (cooperative patients). 5. Patients provide an informed consent Exclusion Criteria: * 1\. Presence of prosthetic crowns. 2. Extensive restorations. 3. Periodontal therapy within the last 12 months. 4. Having surgical therapy or undergoing orthodontic treatment. 5. Ongoing drug therapy that might have an impact on the clinical signs and symptoms of periodontitis. 6\. The use of antibiotics or anti-inflammatory drugs 1 month prior to the procedure and till the end of 3 months of follow-up. 7\. Smokers. 8. Pregnant females. 9. Any known allergies

Locations (1)

Faculty of dentistry ,Cairo university

Cairo, Manial, Egypt

RECRUITING

Outcomes

Primary Outcomes

Clinical Attachment Level

clinical attachment gain by using UNC15 Periodontal probe/ numerical data

Time frame: 3months

Secondary Outcomes

Probing Depth

measuring probing depth by using UNC15 Periodontal probe/numerical data

Time frame: 3 months

plaque index

measuring it visually/numerical data

Time frame: 3 months

Dentinal Hypersensitivity

measuring it using VAS scale

Time frame: 7 days

Bleeding on Probing visually/numerical data

measuring it visually/numerical data

Time frame: 3 months

Central Contacts

Abeer A Barahim, BDS

CONTACT

00201501808068 abeer.barahim@dentistry.cu.edu.eg

Nesma M Shemais, PhD

CONTACT

00201005615697 nesma.shemais@dentostry.cu.edu.eg

Data from ClinicalTrials.gov

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