Determination of Pharmacokinetics of Different Curcuminoids Preparations: Pilot Study

University of Jordan24 enrolled

Overview

This pilot study aims to investigate the pharmacokinetics of a novel curcuminoid preparation with suggested high bioavailability due to its solubility in water, compared to two standard hydrophobic formulations. The findings of this study will help the health care providers and community to select suitable formulation.

This pilot study is the first phase that must be followed, in the second phase, by longer clinical trials to support the findings and investigate the role of the novel preparation on health.The second phase will include an assessment of the effectiveness of several doses of curcumin preparation on health as well as an evaluation of the tolerance and possible adverse effects. The latter could not be evaluated at this stage of a single dose.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

OTHER

Masking

TRIPLE

Enrollment

Conditions

Plasma Levels of Different Curcuminoids Preparations

Interventions

CurcuminDIETARY_SUPPLEMENT

water soluble version of turmeric extract standardized to 10% curcuminoids .

Eligibility

Sex: ALLMin age: 18 YearsMax age: 25 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: Male and female Apparently healthy adults Exclusion Criteria: Postmenopausal women Smokers Overweight Chronic diseases

Locations (1)

The University of Jordan

Amman, Jordan