This study is aimed to investigate the changes in pharmacokinetics and efficacy of antiplatelet agents before and after distal gastrectomy in gastric cancer patients taking oral antiplatelet agents for primary or secondary treatment for cardiovascular disease and to evaluate its impact on the occurrence of postoperative bleeding complications and thromboembolic events.
Study Type
OBSERVATIONAL
Enrollment
20
platelet function testing (Platelet function analyzer-100 (PFA-100) collagen epinephrine closure time, VerifyNowⓇ Assays (aspirin, P2Y12)) before surgery and 5 days, 3 months after surgery
Dept. of Surgery, Kyungpook National University Chilgok Hospital
Daegu, South Korea
RECRUITINGplatelet function testing at 5 days
Difference in the platelet function testing results between before and 5 days after surgery.
Time frame: 5 days
Platelet function testing at 3 months
Difference in the platelet function testing results between before and 3 months after surgery
Time frame: 3 months
postoperative complications
■ incidence of postoperative bleeding and thromboembolic events within 3 months after surgery
Time frame: 3 months
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