Metabolic associated fatty liver disease(MEFLD) is a major chronic liver disease that can lead to various adverse events, such as liver cancer, cardiovascular disease, and chronic kidney disease. The present community-based cohort study enrolls subjects who take health physical examinations at the sub-center outpatient department, Beijing Friendship Hospital. Investigators collect their baseline information, including demographic data, clinical history, physical examination, laboratory results, imageological examination, and so on. Follow-up surveys are conducted annually and the information collected is the same as the baseline. The outcome information, including cardiovascular disease, malignancy, liver cirrhosis, liver decompensation, liver transplantation, and all-cause mortality, are obtained by linking to the hospital discharge database and death registration system of Beijing. The primary aim of the study is to build a risk-stratified evaluation system for MAFLD through the cohort.
The present community-based cohort study enrolls subjects who take physical health examinations at the sub-center outpatient department, Beijing Friendship Hospital. After signing the informed consent, Their previous health physical examination results, which were recorded in the Hospital Information System (HIS) are collected retrospectively. Then, Investigators collect their baseline information, including demographic data, clinical history, physical examination, laboratory results, image logical examination, and so on. Additionally, follow-up surveys will be conducted annually and the information collected is the same as the baseline. The outcome information, including cardiovascular disease, malignancy, liver cirrhosis, liver decompensation, liver transplantation, and all-cause mortality, is obtained from the hospital discharge database and death registration system in Beijing. The study's primary aim is to build a risk-stratified evaluation system for MAFLD through a community population cohort with long-term stable follow-up.
Study Type
OBSERVATIONAL
Enrollment
8,103
Beijing Friendship Hospital, Capital Medical University
Beijing, China
RECRUITINGCardiovascular disease
Incidence of cardiovascular disease during follow-ups
Time frame: 1 to 10 years
Malignancy
Incidence of malignancy during follow-ups
Time frame: 1 to 10 years
Liver cirrhosis
Incidence of liver cirrhosis during follow-ups
Time frame: 1 to 10 years
Liver decompensation
Incidence of liver decompensation during follow-ups
Time frame: 1 to 10 years
Liver transplantation
Incidence of liver transplantation during follow-ups
Time frame: 1 to 10 years
All-cause mortality
Incidence of all-cause mortality during follow-ups
Time frame: 1 to 10 years
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.