The purpose of this study is to assess the safety and tolerability of multiple ascending oral doses of BMS-986322 in healthy participants of Japanese descent.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
24
Specified dose on specified days
Specified dose on specified days
Anaheim Clinical Trials Llc
Anaheim, California, United States
Number of participants with serious adverse events (SAEs)
Time frame: Up to 7 weeks
Number of participants with adverse events (AEs) leading to discontinuation
Time frame: Up to 7 weeks
Number of deaths
Time frame: Up to 7 weeks
Number of participants with AEs
Time frame: Up to 7 weeks
Number of participants with electrocardiogram (ECG) abnormalities
Time frame: Up to 7 weeks
Number of participants with vital sign abnormalities
Time frame: Up to 7 weeks
Number of participants with physical examination abnormalities
Time frame: Up to 7 weeks
Number of participants with clinical laboratory abnormalities
Time frame: Up to 7 weeks
Maximum observed plasma concentration (Cmax)
Time frame: Day 1 and Day 14
Time of maximum observed plasma concentration (Tmax)
Time frame: Day 1 and Day 14
Area under the concentration-time curve within a dosing interval (AUC[TAU])
Time frame: Day 1 and Day 14
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