Antenatal Ultrasound Diagnosis of Periventricular Pseudocysts and Postnatal Outcome

University Hospital, Bordeaux46 enrolled

Overview

The present study aims to improve the information given to the parents during the screening of periventricular pseudocysts in the Pluridisciplinary Center of Prenatal Diagnosis, with retrospective cases screened during the last 5 years in university hospital of Bordeaux.

Antenatal ultrasound screening for periventricular pseudocysts is steadily increasing, enabled in part by technological advances in ultrasound equipment. Most of studies dealing with periventricular pseudocysts and subsequent neurodevelopment are based on neonatal screening, mostly performed in neonatal units. Current data in the literature on the postnatal outcome of children screened antenatally are scarce; there are only 5 cohort studies with small numbers on the subject. The present study aims to improve the information given to the parents during the screening of periventricular pseudocysts in the Pluridisciplinary Center of Prenatal Diagnosis, with retrospective cases screened during the last 5 years in university hospital of Bordeaux.

Study Type

INTERVENTIONAL

Allocation

Purpose

OTHER

Masking

NONE

Enrollment

Conditions

Periventricular Pseudocysts

Interventions

questionnaireOTHER

questionnaire on postnatal development

Eligibility

Sex: ALLMin age: 0 YearsMax age: 5 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Adult patient diagnosed with a periventricular cyst during a prenatal ultrasound at Bordeaux University Hospital between January 1, 2016 and December 31, 2020. * Patient affiliated with or benefiting from a social security plan. * Oral informed consent. Exclusion Criteria: * Subarachnoid cyst * Blake's pouch cyst * Choroid plexus cyst * Periventricular leukomalacia * Poor understanding of French * Patient under legal protection.

Locations (1)

CHU Bordeaux

Bordeaux, France

Outcomes

Primary Outcomes

postnatal child development

composite criterion as follows: Delayed acquisition is defined according to the standards of the Pediatric Society: age of sitting \> 8 months, age of walking \> 18 months, ability or not to associate 3 words at age 3. The use of a medical profession concerns follow-up by a speech therapist, a psychomotrician or a physiotherapist. It is not necessarily a periodic follow-up but a minimum of 2 consultations after the "assessment" consultation. The scoring defines 2 groups, * children with 0 points considered with a "normal" post-natal development * children with 1 point or more considered with a post-natal development disorder.

Time frame: Baseline

Secondary Outcomes

mother's medical history

Time frame: Baseline

medical history of the child

Time frame: Baseline

Data from ClinicalTrials.gov

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