This is a prospective randomised study of the evaluation of the clinical IVF results after invasive PGT-A embryo selection versus Non-invasive PGT-A assisted embryo selection in subfertile women.
A randomized prospective study focusing on subfertile women undergoing IVF treatment followed by embryo transfer on the blastocyst stage. Women assigned to group A proceed to embryo transfer, after invasive PGT-A embryo selection, while women of group B after non-invasive PGT-A assisted embryo selection. IVF outcomes, regarding the success rate of the trasnfer and the time required to achieve conception is studied in both groups.
Study Type
OBSERVATIONAL
Enrollment
200
The basis of embryo selection for transfer: invasive PGT-A or after non-invasive PGT-A
Assisting Nature
Thessaloniki, Thessaloniki, Greece
RECRUITINGEmbryotransfers to conceive
The number of the embryotransfers required for women to conceive
Time frame: Up to the embryotransfer of the last enrolled patient (Dec 2023)
Time interval to conceive
Time interval required for women to conceive (in months): from day of first embryotransfer to positive hCG test
Time frame: Up to the pregnancy test after the last embryo transfer of an enrolled patient (Jan 2024)
Cumulative Live Birth Rate
Cumulative Live Birth Rate achieved after one OPU treatment
Time frame: Up to 38 weeks after the embryo transfer
Abortion rate
The spontaneous miscarriage of women in both groups
Time frame: Up to 2nd trimester miscarriages
DaC rate
The rate of the dilation and curretage rate in both groups
Time frame: during pregnancy according to Greek Law
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