Correction of Post-spinal anesthesia hypotension by fluids pose the risk of volume overload or compromising cardiac conditions. Intravenous Dexamethasone in some studies is used to treat conditions manifested by decrease of peripheral vascular resistance Many advantages were investigated for the addition of dexamethasone to bupivacaine in spinal anesthesia as prolongation of anesthesia time, postoperative analgesia and prophylaxis for shivering. In this study the investigators will investigate the ability of dexamethasone to blunt post-spinal anesthesia hypotension in elderly patients undergoing urological endoscopic surgery, and hence, if it decreases amount of fluids and dose of vasoactive drugs.
Spinal anesthesia is the most consistent block for lower abdomen and lower limb surgery. Spinal anesthesia avoids the risks of general anesthesia such as aspiration of gastric contents and difficulty with airway management. Post-spinal anesthesia hypotension in elderly patients is challenging. Correction of Post-spinal anesthesia hypotension by fluids either colloids or crystalloids or by vasoconstrictors pose the risk of volume overload or compromising cardiac conditions. Intravenous Dexamethasone in some studies is used to treat conditions manifested by decrease of peripheral vascular resistance. Many advantages were investigated for the addition of dexamethasone to bupivacaine in spinal anesthesia as prolongation of anesthesia time, postoperative analgesia and prophylaxis for shivering. Avoidance of complications of opioids is a great issue as, postoperative nausea, vomiting, respiratory depression, urinary retention, prolonged hospital stay and immunosuppression. In this study the investigators will investigate the ability of dexamethasone to blunt post-spinal anesthesia hypotension in elderly patients undergoing urological endoscopic surgery, and hence, if it decreases amount of fluids and dose of vasoactive drugs.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
90
8 mg intrathecally
0.5 % intrathecally
Total amount of fluids
Total amount of fluids needed to maintain mean blood pressure more than 65 mmHg
Time frame: intraoperative
Total amount of vasoactive drugs
Total amount of vasoactive drugs needed to maintain mean blood pressure more than 65 mmHg
Time frame: Intraoperative
Blood pressure
systolic and diastolic blood pressure and mean arterial blood pressure.
Time frame: Intraoperative and up to 1hour postoperative
Post-operative VAS score of pain assessment.
Scores are based on self-reported measures of symptoms that are recorded with a single handwritten mark placed at one point along the length of a 10-cm line that represents a continuum between the two ends of the scale-"no pain" on the left end (0 cm) of the scale and the "worst pain" on the right end of the scale (10 cm).
Time frame: Up to one hour postoperative
Post-operative shivering.
shivering of the patient
Time frame: Up to 6 hours postoperatively.
Post-operative nausea and vomiting.
The presence of nausea or vomiting 6 hours post operatively
Time frame: Up to 6 hours postoperatively.
Post dural puncture headache.
headache during 2 days postoperative and detection of severity and response to treatment
Time frame: Up to 2 days postoperative
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