Genotype-phenotype Association in Hereditary Hemorrhagic Telangiectasia

Inclusion Criteria: * Age between 18 and 75 years. * Confirmed diagnosis of HHT, according to the Curaçao criteria or genetic diagnosis. * Clinically stable condition at the time of inclusion, defined as score \< 7 points on the Epistaxis Severity Score (ESS). * Having signed the informed consent, after having received all the information concerning the study. Exclusion Criteria: * Major coronary or cerebrovascular event in the 3 months prior to inclusion. * Serious intercurrent illnesses, such as acute infections, outbreaks of autoimmune or inflammatory pathology, active cancer, or other pathologies that, at the investigator's discretion, could interfere with the conduct of the study. * Major surgery during the 2 months prior to inclusion. * Pharmacological treatment maintained during the 3 months prior to inclusion with NSAIDs, corticosteroids or chemotherapy. * Toxic habits, including severe smoking, alcohol or drug abuse, which in the opinion of the investigator could interfere with the conduct of the study. * Pregnancy or puerperium. * Any other condition that limits compliance with the visits or procedures established in the protocol.