Drug-coated Balloon Therapy for In-stent Restenosis and de Novo Coronary Lesions

Inclusion Criteria: 1. Patients aged ≥18 years with coronary heart disease; 2. If the target lesion stenosis ≥70% is complicated with angina pectoris or evidence of myocardial ischemia, DCB should be administered; 3. Residual lumen diameter stenosis ≤30% after lesion pretreatment and DCB, no vessel dissection, or type A or B dissection, and TIMI blood flow level 3; 4. Target lesions were treated with DCB for the first time. Exclusion Criteria: 1. Intraoperative implantation of salvage stent in DCB; 2. Acute myocardial infarction occurred within 1 week after DCB operation; 3. Less than 3 months of dual antiplatelet therapy after DCB operation, or more than 1 month of discontinuation of antiplatelet therapy; 4. The position of the stent could not be determined by coronary angiography. 5. Desmovascular disease or left main artery disease; 6. Atrial fibrillation; 7. Patients with severe heart failure, valvular heart disease, renal insufficiency, severe infection and autoimmune disease.