This is a prospective, single-center study of patients with an indication for ventricular pacing who attempted LBBP without electrophysiology recording system (EP system).
Patients who meet the inclusion and exclusion criteria will be enrolled into the study. In the study, the implanter was blinded to EP system, only refer to ECG monitoring. The transition of QRS morphology from S-LBBP (or LVSP) to NS-LBBP, abrupt shortening of Stim-LVAT in lead V5, combined with LV septal-derived PVCs and obvious LBB potential in pacing system analyzer were recorded to help the implanter confirm LBB capture. Meanwhile, the technician recorded the data by EP system and evaluated the consistency of the judgment. The primary endpoints included the success rate, procedure-related information, parameters and complications during 3-month follow-up.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
100
Left bundle branch pacing by a CRT device or dual-chamber pacemaker through the pacing lead at left bundle branch region
First Affliated Hospital, Wenzhou Medical University
Wenzhou, Zhejiang, China
RECRUITINGSuccessful rate
Success rate of left bundle branch pacing without EP system
Time frame: Immediate Postoperative
Judgment coincidence rate
Coincidence rate between the judgment made by the operator through ECG and PSA with EP system.
Time frame: Intraoperative
Intraoperative complications
Intraoperative complications were recorded
Time frame: Immediate Postoperative
Postoperative complications
Postoperative complications were recorded
Time frame: 3 months
Procedure duration
Total time required for operation
Time frame: Immediate Postoperative
Fluoroscopy time
Intraoperative time of radiation use
Time frame: Immediate Postoperative
Change of threshold(V/0.5ms) from immediate postoperative
Threshold for capturing left bundle branch during unipolar pacing
Time frame: 3 months
Change of LVEF(%) from baseline
LVEF changes before and after surgery
Time frame: 3 months
Change of impedance(Ω) from immediate postoperative
Impedance during unipolar pacing
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Time frame: 3 months