Efficacy of Compound Betamethasone Injection Combined With Ropivacaine in Ultrasound-guided Intercostal Nerve Block for Chronic Post-thoracotomy Pain

Affiliated Hospital of Nantong University100 enrolled

Overview

The patients were divided into two groups by random number method: GroupRD1 group and GroupRD2 group were given general anesthesia and intercostal nerve block.The drug for intercostal nerve block was 0.33% ropivacaine +2.333mg compound betamethasone (1.667mg betamethasone dipropionate + 0.667mg betamethasone sodium phosphate) to 15ml.

The RD1 group received ultrasound-guided intercostal nerve block at the incision before anesthesia induction, and the RD2 group received ultrasound-guided intercostal nerve block at the lateral costal Angle before anesthesia induction.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

DOUBLE

Enrollment

100

Conditions

Nerve Block

Interventions

intercostal nerve blockOTHER

General anesthesia and intercostal nerve block were performed. The drug for intercostal nerve block was 0.33% ropivacaine +2.333mg compound betamethasone (1.667mg betamethasone dipropionate + 0.667mg betamethasone sodium phosphate) to 15ml

lateral intercostal nerve blockOTHER

lateral intercostal nerve block

ropivacaine + compound betamethasoneDRUG

The drug for intercostal nerve block was 0.33% ropivacaine +2.333mg compound betamethasone (1.667mg betamethasone dipropionate + 0.667mg betamethasone sodium phosphate) to 15ml

Eligibility

Sex: ALLMin age: 18 YearsMax age: 70 Years

Medical Language ↔ Plain English

Inclusion Criteria: 1. 18-70 years old 2. ASA grade I-III 3. BMI: 18.5-28kg/m2 4. Type of surgery: elective thoracoscopic lung mass resection 5. Informed consent has been signed by the patient and/or family members Exclusion Criteria: 1. game anesthesia or sugar cortical hormone drugs allergic 2. preoperative use of opioid medicines 3. serious blood coagulation dysfunction 4. serious heart, lung, liver and renal insufficiency 5. put, chemotherapy, and glucocorticoid immunosuppressive therapy history or diseases of the immune system 6. peptic ulcer 7. newly gastrointestinal surgery 8. has a history of thoracic surgery 9. is the central nervous system disease 10. Other glucocorticoids should be used with caution in patients such as fractures, wound repair, corneal ulcers, hyperadrenocortical disease, diabetes mellitus, pregnant women, etc.

Locations (1)

YiBinQin

Nantong, Jiangsu, China

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