Efficacy and Safety of Head Acupuncture After Mechanical Thrombectomy for Acute Ischemic Stroke

Xi'an No.3 Hospital272 enrolled

Overview

To evaluate the efficacy and safety of head acupuncture combined with endovascular therapy for cerebral infarction compared with endovascular therapy alone

Control group: Mechanical thrombectomy followed by the guideline recommended treatment for acute ischemic stroke; Experimental group: After mechanical thrombectomy, head acupuncture and the treatment regimen recommended by the guideline for acute ischemic stroke were administered

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

272

Conditions

Acupuncture Acute Ischemic Stroke Mechanical Thrombectomy

Interventions

Scalp AcupunctureOTHER

mplementation plan of head needle: The middle frontal line (MS1), the middle parietal line (MS5) and the back parietal and temporal oblique line (MS7) in the International Standardization Program for the Name of the first needle Point in 1989 were selected, and the needles were inserted along the shape of each section. One needle was inserted into the middle frontal line and the middle parietal line, and two needles were inserted into the back parietal and temporal oblique line. The KWD-808I pulse electrotherapy instrument produced by Changzhou Wujin Great Wall Medical Equipment Co., Ltd. is used on the needle handle after lifting, inserting and twisting. The continuous waveform was used, the voltage was 2-4 V, the frequency was 60-80 times /min, the intensity was tolerated by the patient, the needle was kept for 30min, and the treatment was performed once a day.

The treatment recommended in the guidelines for acute ischemic stroke was administeredOTHER

The treatment recommended in the guidelines for acute ischemic stroke was administered

Eligibility

Sex: ALLMin age: 18 YearsMax age: 100 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Age ≥18 years; * Patients with acute ischemic stroke who received endovascular treatment within 24 hours of onset; * 6 \< NIHSS ≤25; * ASPECT score ≥6 points; * Signed Informed consent. Exclusion Criteria: * CT or brain MRI confirmed intracranial tumor and intracranial hemorrhage; * Contraindications of contrast media; * Dementia or mental illness，unable to cooperate with treatment and follow-up; * The expected survival time was less than 3 months; * Women who are pregnant, planning to become pregnant or breastfeeding; * Currently participating in other clinical trials.

Locations (1)

Xi 'an No.3 Hospital

Xi'an, Shaanxi, China

RECRUITING

Outcomes

Primary Outcomes

Ratio of Modified rankin scale (mRS) score ≤2

The modified rankin Scale (mRS) score ≤2 indicates that the patient has the ability to live independently.

Time frame: 90 days after onset

Secondary Outcomes

National Institute of Health stroke scale(NIHSS) score

NIHSS scores range from 0 to 42, with higher scores indicating more severe nerve damage.

Time frame: 10 days after onset

Modified rankin scale (mRS) score

Modified rankin scale (mRS) Score is used to measure the neurological function recovery status of patients after stroke, and its score ranges from 0 to 6

Time frame: 90 days after onset

Incidence of cerebral hemorrhage

No hemorrhage was found on the first head CT/MRI after cerebral infarction, but intracranial hemorrhage was found on the second head CT/MRI

Time frame: 7 days after randomization

Central Contacts

Shilin L i, Doctor

CONTACT

8615398076154 lihuashiling@126.com

Mingze Chang, Doctor

CONTACT

8615609250898 cbangingze191@163.com

Data from ClinicalTrials.gov

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