Rosacea is a common facial dermatosis, with flares induced by exposome factors. M89PF containing Vichy mineralizing water, probiotic fractions, hyaluronic acid, niacinamide and tocopherol repairs the skin barrier and reinforces skin defences against exposome factors. This study assessed the benefit of M89PF in patients with rosacea associated with erythema and sensitive skin during the Covid-19 pandemic with use of protective face masks.
M89PF was compared to usual skin care in a randomized, split-face study, for 30 days in subjects with rosacea associated with erythema and sensitive skin. Clinical evaluations included erythema, desquamation, skin tightness, dryness, burning sensation, itching, stinging, stinging test, and local tolerability. Instrument evaluations included erythema, skin hydration and TEWL. Subject satisfaction was also assessed.
Study Type
OBSERVATIONAL
Enrollment
20
ISPE
Milan, Italy
erythema
assessment using a chromameter
Time frame: Day 0
erythema
assessment using a chromameter
Time frame: Day 15
erythema
assessment using a chromameter
Time frame: Day 30
skin hydration
using a corneometer
Time frame: Day 0
skin hydration
using a corneometer
Time frame: Day 15
skin hydration
using a corneometer
Time frame: Day 30
transepidermal water loss
tewameter
Time frame: Day 0
transepidermal water loss
tewameter
Time frame: Day 15
transepidermal water loss
tewameter
Time frame: Day 30
clinical symptoms (skin tightness, dryness, burning sensation, itching and stinging)
VAS 0=none to 10=very severe
Time frame: Day 0
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
clinical symptoms (skin tightness, dryness, burning sensation, itching and stinging)
VAS 0=none to 10=very severe
Time frame: Day 15
clinical symptoms (skin tightness, dryness, burning sensation, itching and stinging)
VAS 0=none to 10=very severe
Time frame: Day 30
skin sensitivity
lactic acid skin stinging test
Time frame: Day 0
skin sensitivity
lactic acid skin stinging test
Time frame: Day 15
skin sensitivity
lactic acid skin stinging test
Time frame: Day 30
Demodex density
SSSB method
Time frame: Day 0
Demodex density
SSSB method
Time frame: Day 30
local tolerability
AE questioning
Time frame: Day 15
local tolerability
AE questioning
Time frame: Day 30
subject satisfaction
questionnaire on a scale from 0= very unsatisfied to 5 very satisfied
Time frame: Day 15
subject satisfaction
questionnaire on a scale from 0= very unsatisfied to 5 very satisfied
Time frame: Day 30