Treatment of Moderate FMR During AVR

Fuwai Yunnan Cardiovascular Hospital154 enrolled

Overview

Debates exist on the treatment of moderate functional mitral regurgitation (FMR) in patients undergoing aortic valve replacement (AVR) for aortic valve disease. This study aims to evaluate the left ventricular function, which was evaluated through global longitudinal strain, after isolated AVR and AVR + mitral valve repair (MVr) in this group of patients.

Study Type

OBSERVATIONAL

Enrollment

154

Conditions

Functional Mitral Regurgitation

Interventions

mitral valve repairPROCEDURE

Repair of mitral valve concomitant to aortic valve replacement.

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: 1. Patients who received AVR (with or without concomitant MVr) from two center (Fuwai Yunnan Cardiovascular Hospital and Fuwai Hospital, Chinese Academy of Medical Sciences). 2. Age more than 18 years. Exclusion Criteria: 1. Those with a history of rheumatic valvular disease or infective endocarditis. 2. Primary mitral valve lesions. 3. Patients receiving mitral valve replacement. 4. Patient who refuse to participate in this study, or cannot complete 6-month follow-up after surgery. 5. Age \< 18 years.

Outcomes

Primary Outcomes

left ventricular global longitudinal strain

The change of left ventricular global longitudinal strain compared to before surgery

Time frame: 10/10/2022-10/10/2023

Central Contacts

Xieraili Tiemuerniyazi

CONTACT

+86-18814115887 tiemuernyz@mail2.sysu.edu.cn

Data from ClinicalTrials.gov

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