The aim of the study is to characterize and to quantify SARS-CoV-2 strains in stools, in comparison with the viral strains in respiratory samples, from patients hospitalized for COVID-19. The methods will be standard ddPCR quantifying SARS-CoV-2 RNA and next generation sequencing-whole genome sequencing. The expected results will allow us to better understand SARS-CoV-2 dynamics and compartmentalization, both in the respiratory tract and in digestive-related tissues, according to the evolution of SARS-CoV-2 variants.
Study Type
OBSERVATIONAL
Enrollment
30
PCR and NGS-WGS on stools and respiratory samples
Schvoerer
Vandœuvre-lès-Nancy, France
SARS-CoV-2 dynamics in stools.
Evolutive SARS-CoV-2 dynamics in stools compared to respiratory tract: molecular quantification (ddPCR) of SARS-CoV-2 variants genome in stools, compared to the viral quantification in respiratory samples.
Time frame: 30 monthes
SARS-CoV-2 in stools compared to the virus in wastewaters.
SARS-CoV-2 in stools compared to wastewaters: molecular quantification (ddPCR) of SARS-CoV-2 variants genome in stools, compared to the viral quantification in wastewater samples.
Time frame: 30 monthes
Modelization of SARS-CoV-2 load in stools and COVID-19 global frequency.
SARS-CoV-2 load in stools and COVID-19 global frequency: correlation between SARS-CoV-2 load in stools by ddPCR and COVID-19 incidence in the neighboring global inhabitants population.
Time frame: 30 monthes
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.