Resistance Training With Blood Flow Restriction in Hemophilia

University of Valencia20 enrolled

Overview

The main objectives of this study are to evaluate safety and chronic effects of a low-load resistance exercise intervention (elbow flexions and extensions, and knee extensions) with blood flow restriction in people with hemophilia on quality of life, pain, and on physical and neuromuscular function.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

Conditions

Hemophilia

Interventions

BFRTOTHER

Low-load (30% 1RM) resistance exercise with blood flow restriction

ControlOTHER

Moderate-to-high load (60%-80% 1RM) resistance exercise

Eligibility

Sex: MALEMin age: 18 YearsMax age: 60 Years

Medical Language ↔ Plain English

Inclusion Criteria: * diagnosis of hemophilia A or B and undergoing prophylaxis; * willingness to exercise twice a week during the training program and to complete the pre- and post-program evaluations; * approval by their hematologist to participate in the exercise program; * age between 18 and 60 years; * informed consent signed. Exclusion Criteria: * the inability to attend exercise sessions at least twice a week for 8 consecutive weeks; * non adherence to instruction on proper exercise technique; * surgical procedures performed 6 weeks prior to or during the exercise program; - participation in any other form of exercise, not previously done, during the study; * changes in medication during the study; * a major bleeding episode that posed a risk or prevented exercise; * another hemostatic defect; * need for major surgery; * withdrawal of informed consent.

Locations (1)

Facultat de Fisioteràpia

Valencia, Valencia, Spain

Outcomes

Primary Outcomes

HDsEMG

Change from baseline to the end of the intervention, and the change between the intervention group and the control group.