Interest of an Adapted Physical Activity (APA) Program Among Patients With Juvenile Idiopathic Arthritis: a Feasibility and Efficacy Preliminary Study

Centre Hospitalier Universitaire de Besancon40 enrolled

Overview

The Juvenile Idiopathic Arthritis (JIA) affects joints mobility and leads pain, impacting the practice of physical activities. Adapted Physical Activities are rehabilitation methods increasingly used, but additional studies are needed to define the nature of the physical activity for patients with JIA. The ATHLETIQUE project aims to evaluate the impact of a program integrating APA sessions together with the wearing of a pedometer watch on disease activity of patients with JIA.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

SUPPORTIVE_CARE

Masking

NONE

Enrollment

Conditions

Juvenile Idiopathic Arthritis

Interventions

Adaptated Physical Activity (APA) + pedometer watch

Eligibility

Sex: ALLMin age: 6 YearsMax age: 17 Years

Medical Language ↔ Plain English

Inclusion criteria: * Children (boys and girls) aged 6 to 17 years * Children with juvenile idiopathic arthritis (JIA) : oligoarticular, polyarticular, psoriatic or enthesitis-related arthritis, with more than one year of disease progression * Children on stable conventional or biotherapy 3 months prior to inclusion * Children with a computer/tablet/connected phone that allows them to follow adapted physical activities sessions online * If sexually active adolescents, use an effective method of contraception (oral contraceptives, contraceptive injections, intrauterine devices, double barrier method, contraceptive patches) * Signed informed consent to participate indicating that the parent(s) understand the purpose and procedures required for the study and agree(s) that their child(ren) will participate in the study and abide by the requirements and restrictions of the study * Affiliation with a French social security system or beneficiary of such a system. Non-inclusion criteria: * Treatment by intra-articular infiltration less than 1 month old (immobilization required after the procedure and temporary cessation of physical activity unavoidable) * Contraindications to physical activity * Subject unlikely to cooperate with the study and/or poor cooperation anticipated by the investigator * Subject without health insurance * Pregnant adolescent * Subject in the exclusion period of another study or is the "national volunteer register" Exclusion criteria : * Intra-articular infiltration treatment during the 3 months of the adapted physical activity (APA) program (except for the temporomandibular joint) * Change of biotherapy during the 3 months of the APA program if the treatment is ineffective * Physical inability to engage in physical activity, unrelated to JIA, during the 3-month of the APA program

Outcomes

Primary Outcomes

Juvenile Arthritis Disease Activity-27 Score Assesment

JADAS-27 score includes 4 components : 1. number of inflammatory joints among 27 joints identified, 2. a medical assesment of clinical disease activity with Visual Analogic Scale (from 0 point = worst to 10 points = best), 3. assesment of assesment of patient's well-being by the patient or a parent with Visual Analogic Scale (froom 0 point = worst to 10 points = best), 4. sedimentation rate (from 0 to 10).

Time frame: Week 14

Secondary Outcomes

Juvenile Arthritis Disease Activity-27 Score Assesment

Time frame: Weeks 26 and 50

Evaluation of the physical activity level

The difference of the medium physical activity level is assessed by the continue measures (for 7 days) of the time spent in the MVPA (Moderate to Vigorous Physical Activity) via actimetry (counts/min). Actimetric measurements will be performed before the start of the intervention to determine a value for V0, at 13 weeks (for V1), at 25 weeks (for V2), and at 49 weeks (for V3)

Time frame: Weeks 13, 25 and 49

Evaluation of the physical activity level

The difference of the medium physical activity level is assessed by the number of steps estimated by the pedometer watch (only for the experimental group). Pedometric measurements will be performed throughout the study but collected one week per month to determine a monthly value.

Time frame: Each day during 50 weeks

Quantification of the difference in muscle strength

By dynamometry (Newton)