Comparison of Sedative Effect of Dexmedetomidine and Midazolam for TIVA

Early Phase 1UnknownNCT05574179

Sheikh Zayed Medical College60 enrolled

Overview

Comparison of sedative effects of dexmedetomidine and midazolam using ramsay sedation scores intraoperatively in children undergoing inguinal hernia repair.

a randomized controlled trial to compare the sesative effects of dexmedetomidine and midazolam in pediatric population planned for inguinal herna repair under TIVA in sheikh zayed hospital rahim yar khan.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

HEALTH_SERVICES_RESEARCH

Masking

SINGLE

Enrollment

Conditions

Choosing Better Drug Option for Sedation in Pediatric Population Intraoperatively

Interventions

Dexmedetomidine injectionDRUG

Inj precedex 200mcg in 1ml given in stat doses

MidazolamDRUG

Inj.midazolam 5mg/5ml given in stat doses

Eligibility

Sex: ALLMin age: 6 YearsMax age: 12 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * ASA I and II Age 6 to 12 years Any gender Exclusion Criteria: * ASA III and above Age less than 2 years and above 12 years Congenital heart disease Cardiac arrythmias Congenital abnormalities Respiratory disease Endocrine disorders Mental retardation Organ dysfunction Bleeding disorders Physician or family refusal Previous surgeries Allergy to any drug

Outcomes

Primary Outcomes

Dexmedetomidine is better sedative agent than midazolam in pediatric population

Time frame: 25 minutes

Secondary Outcomes

Midazolam is better sedating agent than dexmedetomidine in pediatric population

Time frame: 25 minutes

Midazolam and dexmedetomidine are equally good sedating agents in pediatric population

Time frame: 25 minutes

Data from ClinicalTrials.gov

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