Xperience™ vs Normal Saline Irrigation Solution for Decreasing Bioburden After Primary Total Hip and Knee Arthroplasty

Inclusion Criteria: * Scheduled to undergo primary total hip (via direct anterior approach, press-fit components) or total knee arthroplasty (via manual approach, cemented components). * Willing to comply with all study-related procedures and be available for the duration of the study. * Provide signed and dated informed consent. Exclusion Criteria: * Unable to provide signed and dated informed consent. * Unwilling or unable to comply with all study-related procedures. * Known history of sensitivity or allergic reaction to any of the study products or its components, including any products used for standard of care (such as dressings or any coverings). * Has underlying condition or state that, in the 'investigator's opinion, would make them too critically ill to complete the day 90 postoperative follow ups. * Pregnant, planning to become pregnant, or nursing female subjects. * Subject with any mental impairment or condition that would make them unable to properly consent without use of LAR or additional subject protections. * Subject is a prisoner and/or part of a vulnerable subject population, which necessitates additional human research subject protections beyond the scope of this protocol. * Subject with an active infection or systemic antibiotic therapy within 2 weeks prior to surgery with the exception of preoperative antimicrobial prophylaxis.