Acne is a chronic condition that typically requires the use of multiple medications.1 Medication adherence is especially challenging for patients with chronic diseases and often decreases over time, especially for those using topical medications.1 Nonadherence can result in multiple negative effects including treatment failure, increased healthcare costs, and decreased quality of life. Primary nonadherence refers to problems acquiring and starting treatment. Challenges to this form of nonadherence include a lack of knowledge, misunderstanding of usage, poor communication with provider, increased cost, and fear of side effects.2 Secondary nonadherence refers to when the patient does not use the medication as prescribed. Hurdles to secondary nonadherence include delayed results, increased complexity of treatment plan, adverse effects, busy lifestyle, and inconvenience.2
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
72
Single topical treatment to be applied daily to area affected once daily.
Two topical treatments to be applied to area affected once daily.
Three topical treatments to be applied to area affected once daily.
Wake Forest University Health Sciences
Winston-Salem, North Carolina, United States
Medication Adherence
Medication adherence measured by recording the weight of medication (in milligrams) in the bottle with electronic monitor attached
Time frame: End of study visit - day 56
Medication Adherence
Medication adherence measured by the data from the electronic monitors by frequency of use recorded by number of times opened
Time frame: End of study visit - day 56
Gender specific adherence (female subjects)
Difference in medication adherence between the male and female subjects. The outcome will compare the two categories in the primary outcome
Time frame: End of study visit - day 56
Gender specific adherence (male subjects)
Difference in medication adherence between the male and female subjects. The outcome will compare the two categories in the primary outcome
Time frame: End of study visit - day 56
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