Effects of Lower Body Positive Pressure in People With Knee Osteoarthritis

Qassim University26 enrolled

Overview

The goal of this clinical trial is to compare effects of retro walking exercise versus forward walking using lower body positive pressure on knee pain, physical function, and quadriceps muscle strength in people with mild to moderate knee OA. The secondary aim is to compare effects of retro walking exercise versus forward walking using lower body positive pressure on mobility function, balance, and self-reported health outcomes in people with mild to moderate knee OA. The main questions it aims to answer are: * Does retro walking exercise improve knee pain, physical function and Quadriceps muscle strength compared to forward walking exercise using lower body positive pressure in people with mild to moderate knee osteoarthritis? * Does retro walking exercise improve Mobility function, balance, and self-reported health outcomes compared to forward walking exercise using lower body positive pressure in people with mild to moderate knee osteoarthritis? Participants will walk (retro versus forward) on a lower body positive pressure treadmill. If there is a comparison group: Researchers will compare \[retro walking compares to forward walking\] to see if \[improve in knee pain, physical function, and quadriceps muscles strength\]

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

Conditions

Knee Osteoarthritis

ExerciseOTHER

Participants will stand on lower body positive pressure treadmill and participate in walking exercise.

Eligibility

Sex: ALLMin age: 40 YearsMax age: 75 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Mild to moderate knee osteoarthritis * Edge bigger or equal 40 years * Knee pain reported by participants in the past 30 days * One or both knees osteoarthritis graded with Kellgren \& Lawrence grade 1 - 3 Exclusion Criteria: * If they didn't meet the inclusion criteria * History of hip, knee or ankle injury or surgery within the last year * Kellgren \& Lawrence grade \> 3 of severe knee OA * Diagnosed with rheumatoid arthritis * History of knee injection with any medicine that reduce pain within the last year * History of other medical condition that would disturb normal walking function * Receive physical therapy in the last three months * Pregnant * Other conditions that are Contra indication to lower body positive pressure.

Locations (2)

Qassim university medical city

Buraidah, Almuledia, Saudi Arabia

RECRUITING

Medical City in Qassim University

Buraidah, Saudi Arabia

RECRUITING

Outcomes

Primary Outcomes

Numeric pain rating scale

The NPRS is an 11-point scale with "0" representing "no pain" and "10" representing "most imaginable pain" used to assess pain intensity.

Time frame: Change from baseline pain at 6 weeks

Knee injury and osteoarthritis outcome score (KOOS)

The KOOS is a self-reported, knee-specific questionnaire that is aimed to measure knee pain, symptoms, and level of disability during the last week.

Time frame: Change from baseline pain, symptoms, and level of disability at 6 weeks.

Thigh muscle strength test

A Biodex isokinetic dynamometer (Model 4Pro) connected to a computer will be used to assess bilateral knee's flexor and extensor isometric muscle strength.

Time frame: Change from baseline thigh muscle strength at 6 weeks.

Secondary Outcomes

Five times sit to stand test

The FTSST is used to assess lower extremity strength and balance and is an indicator of postural control.

Time frame: Change from baseline balance at 6 weeks.

3-M Backward Walk Test

Patients will be instructed to walk backwards when the assessor says "go" and stop when the participant pass the end line colored tape. The participant will be allowed to look back.

Time frame: Change from baseline backward walking at six weeks.

Timed up and go test

The TUG assesses functional mobility by assessing an individual's ability to stand up, walk 3 meters at a comfortable pace, turn 180 degrees, walk back 3 meters, and sit down

Time frame: Change from baseline Functional mobility at six weeks.

4 square step test

The test is designed to assess dynamic balance and coordination.

Time frame: Change from baseline dynamic balance and coordination at six weeks

Functional reach test

FRT used to assess participant's stability and balance by measuring the maximum distance participant can reach forward while standing in fixed position.

Time frame: Change from baseline static balance at six weeks

10-Meter Walk Test

The 10-MWT evaluates walking speed over a short duration with or without an assistive device.

Time frame: Change from baseline walking speed at six weeks

6 minute walk test

6MWT assesses the distance walked over 6 minutes as a test of aerobic capacity and endurance.

Time frame: Change from baseline aerobic capacity and endurance at six week

Medical Outcomes Study Short Form 12 (SF-12)

It is a health survey that evaluates health related quality of life in a clinical practice and research purpose

Time frame: Change from baseline quality of life at six weeks

Patient Health Questionnaire -9

PHQ-9 is an instrument to evaluate depression symptoms among different populations.

Time frame: Change from baseline depression at six week

Rapid Assessment of Physical Activity

RAPA is a 9-items, self-reported questionnaire measures the levels of physical activity of adult older than 50 years.

Time frame: Change from baseline physical activity at six week

Central Contacts

Sattam M Almutairi, Ph.D

CONTACT

+966505102644 A.sattam@qu.edu.sa

Data from ClinicalTrials.gov

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