Muscle Activation With Acute Bouts of Blood Flow Restricted Resistance Exercise

Inclusion Criteria: 1. Capable and willing to give written informed consent 2. Capable of understanding inclusion and exclusion criteria 3. 18-40 years of age 4. A waist circumference \< 40 inches. 5. No medical condition that would limit their participation in supervised exercise sessions based on the Physical Activity Readiness Questionnaire for Everyone (PARQ+) 6. No current prescription medications 7. Willing to allow researchers to use data and images (e.g., Dual Energy X-Ray Absorptiometry) for research purposes after study participation is completed 8. Either untrained or resistance-trained by the following definitions: Untrained individuals are considered those that report less than two days per week of structured (\> 30 minutes) moderate to vigorous-intensity aerobic exercise and less than two days per week of structured resistance training for the 3 months prior to study start. Resistance-trained individuals are considered those who report performing structured moderate to intense resistance exercise for at least three days per week for at least 2 years prior to study start. Exclusion Criteria: 1. Self-report history of diabetes mellitus 2. Self-report history of cardiovascular, peripheral vascular, cerebral vascular, pulmonary, or renal disease 3. Self-report or evidence of uncontrolled hypertension \> 150/85 (or measured) 4. Self-report history of blood clotting disorders 5. Self-report history of deep vein thrombosis or pulmonary embolism 6. Self-report history of sickle cell trait 7. Self-report history of varicose veins 8. Self-report history of a myopathy leading to muscle loss, weakness, severe cramps or myalgia 9. Self-report history of orthopedic limitations that would preclude them from participation in a dynamic exercise program 10. Self-report history of musculoskeletal disorders (e.g., severe osteoarthritis, rheumatoid arthritis, avascular necrosis or osteonecrosis) 11. Self-report history of neurological disorders (e.g., peripheral neuropathy, amyotrophic lateral sclerosis, multiple sclerosis, fibromyalgia, Parkinson's disease) 12. Weight loss of \> 10% in the last 3 months prior to screening 13. Active tobacco use including smoking, vaping, or smokeless tobacco use 14. Current consumption of \> 14 alcoholic drinks per week based on self-report 15. Any other condition that, in the judgement of the Principal Investigator and/or the Medical Director of this protocol, may interfere with study participation and adherence to the protocol