Thoracic surgery is one of the surgeries where postoperative pain is intense. In this study, the investigators aimed to compare the efficacy of two different intrathecal morphine doses administered for postoperative analgesia according to patients' ideal body weight.
Patients who underwent video-assisted thoracic surgery were divided into two groups: 10 mcg/kg and 7 mcg/kg intrathecal morphine for postoperative analgesia. Intraoperative and postoperative hemodynamic variables, postoperative morphine consumption, postoperative pain scores, side effects and additional analgesic requiretment were recorded.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Enrollment
46
In the literature, intrathecal morphine doses were applied according to the patients' actual body weight and there is no study comparing intrathecal morphine dose in thoracic surgery patients.
Cukurova University
Adana, Turkey (Türkiye)
pain scores
Postoperative pain scores of the patients were recorded via Visual Analog Scale (VAS; 0= no pain, 10= worst pain)
Time frame: Change from baseline pain scores at 24 hours
morphine consumption
At the end of surgery, patients were allowed to use the patient controlled analgesia (PCA) device. The PCA delivered bolus doses of morphine (0.02 mg/kg) every 10 minutes without a backround infusion. Morphine consumption (mg) was evaluated and recorded postoperative 24 hours.
Time frame: Change from baseline morphine consumption at 24 hours
systolic arterial blood pressure
Intraoperative systolic arterial blood pressure (mmHg) values were recorded during surgery.
Time frame: change from baseline systolic blood pressure at 150 minutes
diastolic arterial blood pressure
Intraoperative diastolic arterial blood pressure (mmHg) values were recorded during surgery.
Time frame: change from baseline diastolic blood pressure at 150 minutes
mean arterial blood pressure
Intraoperative mean arterial blood pressure (mmHg) values were recorded during surgery.
Time frame: change from baseline mean arterial blood pressure at 150 minutes
heart rate
Intraoperative heart rate (beats/minute) values were recorded during surgery.
Time frame: change from baseline heart rate at 150 minutes
side effects
All of patients were visited in the thoracic surgery ward after surgery and side effects were evaluated and recorded.
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Time frame: postoperative 24 hours