COPD causes an acute deterioration of respiratory symptoms, particularly increased breathlessness and cough, and increased sputum volume and/or purulence. Worsening airflow limitation is associated with an increasing prevalence of exacerbations and risk of death. These exacerbations can range from self-limited diseases to episodes of florid respiratory failure requiring mechanical ventilation .Hospitalization for COPD patients post COVID is associated with poor prognosis with increased risk of death. Hence techniques of efficient clearance of peripheral airways may reduce airway occlusion by excess mucus and inflammatory cells, improving lung function, exercise capacity and reducing exacerbation frequency.
Patients were assigned to 2 groups with pre- and post- treatment protocol application. All patients were thoroughly evaluated before and after treatment protocol application. Thirty patients (Group A) received high frequency chest wall oscillation with vest system in addition to their prescribed medication, 3 times per week for three successive weeks and the total duration of each session was 15-30 minutes. Thirty patients (Group B) received Lung flute (OPEP) in addition to their prescribed medication, 2 times per week twice a day for three successive weeks and the total duration of each session was 10-15 minutes
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
60
Patients were assigned to 2 groups with pre- and post- treatment protocol application. All patients were thoroughly evaluated before and after treatment protocol application.
. Thirty patients (Group B) received Lung flute (OPEP) in addition to their prescribed medication, 3 times per week twice a day for three successive weeks
Cairo University
Cairo, Egypt
RECRUITINGForced vital capacity (FVC)
FVC is the amount of air that can be forcibly exhaled from lungs after deepest inspiration, it's measured by spirometry
Time frame: Forced vital capacity (FVC)will be measured at baseline, and after three weeks.
Forced expiratory volume in one second (FEV1)
FEV1 is the maximum amount of air that the subject can forcibly expel during the first second following maximal inhalation
Time frame: FEV1 will be measured at baseline, and after three weeks.
FEV1/FVC ratio
The FEV1/FVC is a ratio that reflects the amount of air you can forcefully exhale from your lungs. It's measured by spirometry, a test used to evaluate lung function
Time frame: FEV1/FVC ratio will be measured at baseline, and after three weeks.
The forced mid-expiratory flow (FEF25-75%)
(FEF25-75) measures the average flow rates of medium-to-small airways during the forced vital capacity (FVC).it' is a potentially sensitive marker of obstructive peripheral airflow
Time frame: (FEF25-75%) will be measured at baseline, and after three weeks.
Six-minute walk test
Six-minute walk test was carried out before and after interventions to determine the patient functional capacity
Time frame: 6min walk test will be measured at baseline, and after three weeks.
COPD assessment test (CAT
is a validated, short (8-item) and simple patient completed questionnaire
Time frame: COPD assessment test (CAT)will be measured at baseline, and after three weeks.
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