Iron Deposits in the Pancreas by MRI Method of Dialysis Patients With Hemosiderosis Iatrogenic (ERDFP)

Ramsay Générale de Santé185 enrolled

Overview

Recently, a multidisciplinary scientific conference proposed to consider iron overload in dialysis patients as pathological only in the event of demonstration of radiological (in MRI), pancreatic or cardiac ferric deposits. In this context, the aim of the proposed scientific study is to demonstrate the presence of ferric deposits in the pancreas by T2\* MRI in dialysis patients with radiological hepatic iron overload, particularly in cases of moderate and severe iron overload.

Study Type

OBSERVATIONAL

Enrollment

185

Conditions

Iron Deposition Dialysis Iatrogenic Hemosiderosis

Interventions

MRIPROCEDURE

Pancreatic MRI

Medical Language ↔ Plain English

Inclusion Criteria: * Male, female, over 18 years old * Patient on hemodialysis or peritoneal dialysis at the Claude Galien Private Hospital * Patient on dialysis who has undergone one (or more) abdominal MRI for iron quantification * Patient who has signed a non-objection form for the retrospective use of their MRI, medical and biological data for the purpose of scientific study Exclusion Criteria: * Patient who has signed a form to object to the use of their health data * Pregnant woman * Poor adherence to the dialytic technique * Severe cognitive impairment * Hepatic cirrhosis * Frank inflammatory syndrome or an active infectious disease * Genetic hemochromatosis and transfusion hemosiderosis of hemoglobinopathies and hematological diseases * Recent major bleeding (\< 3 months) * Recent major surgery (\< 3 months) * Transfusion dependence * Progressive malignant disease * Pacemakers incompatible with an MRI and metal heart valves

Outcomes

Primary Outcomes

Presence of pancreatic iron deposit

Presence of pancreatic iron deposits as a function of hepatic iron level during iron overload in the dialysis patient will be evaluated from the pancreatic iron concentration measured by MRI and expressed by a T2\* value in ms.

Time frame: 1 day