Platelet Rich Fibrin Versus Melatonin Around Dental Implants

Misr University for Science and Technology30 enrolled

Overview

Dental implant is a dental treatment that allow oral rehabilitation for partial and fully edentulous patients. Osteointegration is the factor that control success s or failure of dental implant that can be improved by addition of different adjunctive biological materials. Platelets Rich fibrin plays a significant role in tissue regeneration and wound healing. Melatonin is biological hormone that secreted from pineal gland and played an important role in human growth.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

SINGLE

Enrollment

Conditions

Patients With Missing Teeth

Interventions

dental implants with melatonin gelBIOLOGICAL

platelet rich fibrin membrane around dental implants

Eligibility

Sex: FEMALEMin age: 18 YearsMax age: 60 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: 1. good oral hygiene participants, 2. free of any systemic diseases, 3. Patients' age ranged from 20 to 40 years old. 4. Patients who can complete surgery and the study protocol. 5. Partially edentulous patients in the posterior mandibular region (at least a single-mandibular edentulous area) with periodontal health. Exclusion Criteria: 1. patients who had parafunctional habits, 2. current and former smokers, pregnant 3. lactating women 4. unmotivated patients 5. patients with psychological problems 6. patients who were not able to follow the treatment protocol -

Locations (1)

Faculty of dentistry at MUST

Giza, Egypt

Outcomes

Primary Outcomes

gingival thickness

Time frame: 6 months

Secondary Outcomes

bone density

Time frame: 6 months

marginal bone loss

Time frame: 6 months

Data from ClinicalTrials.gov

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