Anxiety Before Non-cardiac Surgery in Adults

Inclusion Criteria: 1. patients undergoing elective with general anesthesia surgery (gynecologic oncology, general surgery, orthopedics and urinary); 2. The estimated operation time is more than 2 hours. 3)18≤ age ≤ 80; 4)be able to communicate normally in daily life, without serious hearing and visual impairment; 5)ASA:I-II; 6)sign informed consent and volunteer to participate in this study. Exclusion Criteria: 1. Having a history of brain diseases, such as stroke, epilepsy, psychosis other history of neuropsychiatry. 2. Patients with serious diseases of heart, liver, lung, kidney or other organs. 3. Having a definite diagnosis of cognitive impairment, such as Alzheimer's disease; 4. Those who use sedatives before evaluation in this study; 5. Drug addicts; 6. Alcoholics; 7. pregnant women; 8. participated in other clinical trials as a subject in the past 3 months.