Facial Skin Clinical and Microbial Profiling From Oral Probiotic Supplementation

Inclusion Criteria: * Healthy volunteers * Fully informed with the study specifications. * Signed consent form prior to commencing the study. * Motivated for participation in the study, and available over the full test period. * Healthy skin on the face (i.e., absence of psoriasis, eczemas, erythema, oedema, scars, wounds, lesions, or any other type of inflammatory or autoimmune skin condition). * Healthy gut (i.e., absence of irritable bowel diseases (IBD), irritable bowel syndrome (IBS), or any other type of inflammatory or autoimmune gut condition). * No supplementation with probiotic, prebiotic or synbiotic products 2 weeks prior and/or during the whole study period. * No supplementation with niacin (vitamin B3) 2 weeks prior and/or during the whole study period. * No significant change in skin care routine (such as injectable cosmetics, skin tanning, etc.) throughout the whole study period. * No significant change in the diet throughout the whole study period. Exclusion Criteria: * Not fulfilling the inclusion criteria. * Pregnant or lactating 3 months prior to study commencement or during the study. * Women post menopause. * Use of antibiotics at least 4 weeks prior and/or during the whole study period. * Sun-tanned facial skin. * Participating in another clinical study that could interfere with the present research. * Presented health problems or specific medications that could adversely affect the study outcome. * Presented any cutaneous hypersensitivity or allergy to cosmetic products. * Major surgery on the face one year prior to study commencement. * Applied any cleansing, topical or moisturizing product (including all make-up products) to the measurement area the morning of assessments at Oriflame Cosmetic AB. * Exposure to artificial UV light and/or to the sun during the study. * Special diets (vegan, low carbohydrate, weight loss diet, etc.). * Significant change in weight one month before or during the study period.