The purpose of this study is to examine changes in perceived daily performance and executive functioning following chemotherapy in individuals with non-central nervous system cancers.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
38
Standard chemotherapy protocols for adjuvant \& neoadjuvant treatment for different types of solid malignancies
Bnai Zion Medical Center
Haifa, Israel
RECRUITINGChange in scores of Canadian Occupational Performance Measure.
Canadian Occupational Performance Measure - COPM assesses perceived daily performance and performance satisfaction with meaningful daily activities. During the pre-chemotherapy assessment, participants will identify up to five activities that they prioritize as meaningful for them. Each of these activities is then rated on a 10-point scale for perceived performance (1=not able to do at all, 10=able to do extremely well) and similarly for satisfaction with performance. The final scores of the COPM are the average scores for total performance and for satisfaction (higher scores indicate better performance or satisfaction with performance). During the post-chemotherapy assessment, the participants will rate the same activities they prioritized in the pre-chemotherapy assessment.
Time frame: Change between Pre-to post (three months) chemotherapy
Reintegration to Normal Living index.
Assesses daily participation in recreational and social activities, movement within the community, and degree of comfort the individual has in his/her role in the family and with other relationships.
Time frame: Change between Pre-to post (three months) chemotherapy
Backward Digit Span.
Assesses working memory capacity
Time frame: Change between Pre-to post (three months) chemotherapy
Dual Tasking by performing two tasks concurrently (motor by the Box & Blocks Test and cognitive by backward subtraction for one minute)
Assesses dual tasking by performing two tasks concurrently
Time frame: Change between Pre-to post (three months) chemotherapy
Color Trail Test - CTT
Assesses cognitive flexibility
Time frame: Change between Pre-to post (three months) chemotherapy
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Cognitive performance-based assessment will be assessed by the Weekly Calendar Planning Activity.
A performance-based assessment that examines the influence of subtle executive function difficulties on person's ability to perform a multiple-step activity.
Time frame: Change between Pre-to post (three months) chemotherapy
Cognitive Self Efficacy FACT-Cognitive Function questionnaire
FACT-Cognitive Function questionnaire Version 3 assesses cognitive functioning in individuals with cancer. For assessing cognitive self-efficacy we will use the cognitive self-abilities subscale (CogPCA) of the questionnaire, which includes 7 statements with responses given on a 5-point Likert scale (from 0, never; to 4, several times a day). The score range= 0-28 with higher scores indicating higher difficulties.
Time frame: Change between Pre-to post (three months) chemotherapy
Emotional Well-Being FACT-G questionnaire
Emotional Well-Being will be assessed by the emotional well-being subscale from the FACT-G (General) questionnaire (https://www.facit.org/). The EWB scale includes six statements with responses given on a 5-point Likert scale (from 0, not at all; to 4, very much). The score range= 0-24 with higher scores indicating higher emotional deficits.
Time frame: Change between Pre-to post (three months) chemotherapy
Functional Assessment of Chronic Illness Therapy - Fatigue (FACIT-F)
Fatigue will be assessed by the FACIT Fatigue questionnaire FACIT-F, Version 4 which includes 13 statements with responses given on a 5-point Likert scale (from 0, not at all; to 4, very much). The score range= 0-52 with higher scores indicating more fatigue.
Time frame: Change between Pre-to post (three months) chemotherapy
Qualitative open-ended questions regarding perceived changes in participants' cognitive functioning following cancer diagnosis and how these changes affect their daily functioning
Open ended questions will be presented on a sheet of paper and the participants will be asked to write their answers bellow together with the accessor. Reporting does not include a score on a scale.
Time frame: Pre chemotherapy
Qualitative open-ended questions regarding perceived changes in participants' cognitive functioning following chemotherapy and how these changes affect their daily functioning
Open ended questions will be presented on a sheet of paper and the participants will be asked to write their answers bellow together with the accessor. Reporting does not include a score on a scale.
Time frame: Post (three months) chemotherapy