Povidone Iodine Irrıgation at Hip-Knee Arthroplasty

Ankara University120 enrolled

Overview

Povidone iodine (PI) solution is an antimicrobial solution that can be used at hip and knee arthroplasty cases. It contains iodine that may be absorbed by the body. This study aims to investigate any absorption caused by PI solution.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

SCREENING

Masking

DOUBLE

Enrollment

120

Conditions

Osteoarthritis Hyperthyroidism Iodine Toxicity

Interventions

PI solutionPROCEDURE

3,000 cc of \<2% concentrated povidone iodine solution will be used as irrigation solution at primary hip/knee arthroplasty. The PI solution was left in the joint for 3 minutes.

Saline SolutionPROCEDURE

3,000 cc of 0.9% saline solution will be used as irrigation solution at primary hip/knee arthroplasty. The saline solution was left in the joint for 3

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * All patients with hip/knee osteoarthritis who undergo primary arthroplasty Exclusion Criteria: * Patients with abnormal thyroid function tests in the preoperative period, a history of the previous thyroid-related disease.

Locations (1)

Ankara University Faculty of Medicine

Ankara, Turkey (Türkiye)

RECRUITING

Outcomes

Primary Outcomes

Urine iodine level

Urine iodine concentration

Time frame: postoperative first day

Secondary Outcomes

Thyroid hormone

Blood thyroid hormone levels including: TSH, T3 and T4

Time frame: postoperative 14 days

Central Contacts

Hakan Kocaoglu, MD

CONTACT

00903125082321 kocaoglu@ankara.edu.tr

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.