Detection of Microplastics in Cardiac Surgery Patients

Kun Hua40 enrolled

Overview

The exponential growth in plastic production/use translates into a parallel increase in environmental plastic waste, which is constantly degraded into microplastics and nanoplastics. Information on the effects of microplastics on human health is still preliminary. Cardiac surgery patients is a population high exposed to plastics. This observational study will obtain biological samples of cardiac surgery patients as a reference and vulnerable group of individuals highly exposed to microplastics and potentially more susceptible. The objective of this research is to be able to detect microplastics on blood and operation samples of cardiac surgery patients as well as their potential genotoxic and immunological damage.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Cardiac Surgery Microplastics Nanoplastics Cardiovascular Diseases

Interventions

Eligibility

Sex: ALLMin age: 18 YearsMax age: 80 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Age ≥18 years * Elective cardiac surgery Exclusion Criteria: * Emergency surgery or limited-term surgery * Previous cardiac surgery * Previous severe liver disease * Pregnant or planning to become pregnant * Have a malignant tumor

Outcomes

Primary Outcomes

Detection of microplastics in human heart tissue and the blood

Detection of microplastics in human heart tissue and the blood undergoing cardiac surgery

Time frame: perioperative: preoperative and pro-/postoperative blood and intraoperative heart tissue