The Effectiveness of Single Antibiotic Paste Nitrofurantoin Versus Double Antibiotic Paste

Altamash Institute of Dental Medicine60 enrolled

Overview

In our study, we used nitrofurantoin as a root canal medication in patients suffering from symptomatic irreversible pulpitis in alleviating pain compared with double antibiotic paste.

This study aims to compare the efficacy in alleviating pain between intracanal medicaments Nitrofurantoin versus double antibiotic paste.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

Conditions

Pain Symptomatic Irreversible Pulpitis

Interventions

NitrofurantoinDRUG

Nitrofurantoin has been found to successfully eradicate gram-negative bacteria such as Enterococcus faecalis that one of the most important bacteria in endodontic lesions

Double AntibioticDRUG

DAP is a combination of two antibiotics which are ciprofloxacin and metronidazole

Eligibility

Sex: ALLMin age: 18 YearsMax age: 50 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * No medical history * no history of allergy to medications used in root canal treatment * patients suffering from Symptomatic Irreversible Pulpitis Exclusion Criteria: * Patients who were not suitable for conventional root canal treatment * multirooted teeth

Locations (1)

Hira Danish

Karachi, Sindh, Pakistan

Outcomes

Primary Outcomes

To alleviate dental pain

Dental pain will be measured by using Visual Analogue Scale(VAS) which is an 10-point scale from 0-10 where 0 represents no pain and 10 represents the worst pain measured

Time frame: 12 hours upto 72 hours following placement of intracanal medicament

Data from ClinicalTrials.gov

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