The investigators aim is to compare outcomes between an angled-tip guidewire and a straight-tip guidewire in cannulation of the common bile duct during ERCP. This is a randomized, controlled, single-blinded study. The primary outcome is success of cannulation and secondary outcomes are incidence of post-ERCP pancreatitis, procedure duration, and rate of complication between the angled wire and straight wire.
Wire-guided cannulation of the common bile duct is a standard technique utilized during Endoscopic Retrograde Cholangio-Pancreatography (ERCP) to ensure safe and effective access to the common bile duct via the ampulla of Vater. Due to the anatomy of the ampulla, and the orientation of the biliary orifice, a guidewire with an angled tip may allow easier and safer access to the common bile duct without inadvertent manipulation of the pancreatic duct. The investigators aim to assess the technical and clinical outcomes between an angled-tip guidewire (GW) compared to a straight-tip guidewire in wire-guided cannulation of the common bile duct. The investigators hypothesize that an angled-tip GW is associated with increased rate of successful cannulation, decreased procedure time and decreased rate of post-ERCP pancreatitis in wire-guided biliary cannulation during ERCP.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
70
Cannulation of the common bile duct using an angled-tip guidewire during ERCP
Cannulation of the common bile duct using an straight-tip guidewire during ERCP
Lahey Hospital and Medical Center
Burlington, Massachusetts, United States
Cannulation
Rate of successful cannulation of common bile duct
Time frame: Day of Procedure
Post ERCP Pancreatitis
Number of participants who develop post ERCP pancreatitis
Time frame: Procedure day and up to day 5 post procedure
Duration
Total duration of procedure
Time frame: Day of procedure
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.