The purpose of this study is to map the acute, short-term cortical evoked responses to thalamic electrical stimulation in persons with intractable epilepsy
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
BASIC_SCIENCE
Masking
NONE
Enrollment
25
This will be performed to study the EEG responses to DBS/RNS stimulation electrical pulses. The stimulation frequencies will be sequentially increased and each stimulation will last for 2 minutes.There will be a 1-2 minute wash out period after each trial.
The University of Texas Health Science Center at Houston
Houston, Texas, United States
RECRUITINGChange in amplitude of evoked potentials metrics as assessed by the scalp EEG
Time frame: Baseline, Intra intervention (about 20 minutes after baseline)
Change in amplitude of evoked potentials metrics as assessed by the scalp EEG
Time frame: Baseline, post intervention (about 2 hours after baseline )
Change in latencies of evoked potentials and phase synchronization metrics recorded as assessed by the scalp EEG
Time frame: Baseline, Intra intervention (about 20 minutes after baseline)
Change in latencies of evoked potentials and phase synchronization metrics recorded as assessed by the scalp EEG
Time frame: Baseline, post intervention (about 2 hours after baseline )
Change in reaction time to visual stimuli measured as vigilance score assessed by the Psychomotor Vigilance test (PVT)
This is a computerized testing that will record errors in being unable to tap a switch/button
Time frame: Baseline, Intra intervention (about 20 minutes after baseline)
Change in reaction time to visual stimuli measured as vigilance score assessed by the Psychomotor Vigilance test (PVT)
This is a computerized testing that will record errors in being unable to tap a switch/button
Time frame: Baseline, post intervention (about 2 hours after baseline)
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.