Cross-sectional observational study of the relationship between speech patterns and psychiatric symptoms and disorders.
Major psychiatric disorders often occur together in the same patient and it can be difficult to distinguish between disorders with overlapping symptoms. The majority of patients with mental illness receive treatment in settings where it is not feasible to conduct detailed diagnostic interviews or neuropsychiatric testing. A cost-effective and efficient tool is needed for accurate diagnosis. Looking at language is an efficient way of making sense of the brain because it is easily observed and reflects brain circuitry. Automated natural language processing (NLP) can help us do this objectively, efficiently, and with high sensitivity. The investigators aim to use linguistic features extracted using natural language processing to aid in diagnostic classification and in predicting dimensional symptoms. This will be done by obtaining clinical diagnoses, language samples, and self-report scales from 604 participants with a variety of psychiatric symptoms. Adolescents will also be included and the investigators will try to predict diagnosis in adolescents using models that were built on adult data.
Study Type
OBSERVATIONAL
Enrollment
255
Digital assessment of speech and language abilities
Zucker Hillside Hospital
Glen Oaks, New York, United States
Speech features from the Winterlight Speech Assessment
Acoustic and linguistic measures of speech computed based on performance on the Winterlight Speech Assessment
Time frame: Baseline
Brief Symptom Inventory
53 item. Range = 0, not at all - 4, extremely. Higher scores resulting in worse outcome. TLC: Scale for the Assessment of Thought Language and Communication
Time frame: Baseline
Patient Health Questionnaire - 9
9 item. Range = 0, not at all - 3, nearly every day. Higher scores resulting in worse outcome.
Time frame: Baseline
Generalized Anxiety Disorder - 7
7 item. Range = 0, not at all - 3, nearly every day. Higher scores resulting in worse outcome.
Time frame: Baseline
Prodromal Questionnaire - Brief
18 item. Range = 0, no - 1, yes. Higher scores resulting in worse outcome.
Time frame: Baseline
Scale for the Assessment of Thought Language and Communication
20 item, range= 0, absent - 3, severe; higher scores resulting in worse outcome.
Time frame: Baseline
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