Heart failure (HF) affects about 1% of patients younger than 55 years, whereas the prevalence of HF increases \> 10% in patients with at least 70 years of age. Despite HF with reduced ejection fraction (HFrEF) and HF with preserved ejection fraction (HFpEF), the clinical significance of HF with mildly reduced ejection fraction (HFmrEF) has gained more importance within the past years. Those patients are characterized by a left ventricular ejection fraction (LVEF) of 41-49%. However, within the current European guidelines, limited treatment recommendations in this subgroup of HF are yet available as a consequence of the limited number of studies in this field. The "Heart Failure With Mildly Reduced Ejection Fraction Registry" aims to characterize patients with HFmrEF and investigated the prognostic impact of interventional and pharmacological therapies in this subgroup of HF patients.
Study Type
OBSERVATIONAL
Enrollment
2,200
University Medical Centre Mannheim
Mannheim, Germany
All-cause mortality
All-cause mortality
Time frame: 2 years.
Change of LVEF
Change of LVEF
Time frame: 2 years.
Change of NT-pro BNP
Change of NT-pro BNP
Time frame: 2 years.
Heart-failure related hospitalization
Heart-failure related hospitalization
Time frame: 2 years.
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