Salivary Alkaline Phosphatase as a Biomarker for Dental Caries in A Group of Egyptian Children With Different Growth Rates: A Descriptive Cross-Sectional Study

Cairo University21 enrolled

Overview

Aim of the study: 1. Assess the correlation between salivary alkaline phosphatase levels and dental caries. 2. Assess the effect of growth of children on the levels of salivary alkaline phosphatase enzyme. 3. Assess the effect of growth of children on caries experience and severity.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Dental Caries in Children

Interventions

No interventionOTHER

There is no intervention as this is an observational study

Eligibility

Sex: ALLMin age: 6 YearsMax age: 8 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Children aged 6 to 8 years old. * Children with and without previous dental visits. Exclusion Criteria: * Children with any systemic or mental illness. * Children whose parents refuse to sign the informed consent. * Children who will not cooperate on participation

Outcomes

Primary Outcomes

Salivary Alkaline Phosphatase levels in children with and without dental caries

Measured by spectrophotometry (unit: U/L)

Time frame: 2 months

Secondary Outcomes

Caries index

Measured by DMFT and deft (unit: scores)

Time frame: 2 months

Caries severity

Measured by ICDAS (unit: scores)

Time frame: 2 months

Data from ClinicalTrials.gov

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