Safety and Efficacy of Injectable Poly-L-Lactic Acid for Volume Loss in the Temples Using Dual Plane Injections

Inclusion Criteria: * Subjects who are able to give voluntary, written informed consent to participate in this study and from whom consent has been obtained including HIPAA authorization * Healthy males or females over 25 years old with temporal hollows volume deficit of Grade 2 to 4 on the Galderma Temple Volume Deficit Scale * Subjects with Fitzpatrick photo skin types I-IV * Subjects who agree not to have any procedures affecting facial wrinkles (e.g. filler, botulinum toxin, radiofrequency, laser, intense-pulsed light, ultrasound) for the duration of the study * Subjects who do agree not to have any other procedures affecting skin quality (microdermabrasion, peels, acne treatments, etc.) for the duration of the study * Subjects who understand this study and are able to follow study instructions and are willing to attend the required study visits * Subjects who agree to be photographed for research reasons and their identity may not be concealed in these photographs. Exclusion Criteria: * Subjects who are pregnant, planning to become pregnant or breastfeeding. A urine pregnancy test will be done to rule out pregnancy * Subjects of child-bearing potential who are not using an approved method of birth control (oral contraceptives, intrauterine device, contraceptive implant, barrier methods with spermicide or abstinence). Females of non-childbearing potential are defined as post-menopausal (absence of menstrual bleeding for one year), hysterectomy or bilateral oophorectomy. * Subjects who cannot understand or are not willing to comply with the requirements of the study * Subjects who have a known allergy to poly-L-lactic acid, carboxymethylcellulose, non-pyrogenic mannitol or any anesthetic * Subjects who have taken any NSAIDs (aspirin, ibuprofen, etc.) within 7 days before treatment * Subjects who have taken acetaminophen 24 hours before treatment * Subjects who have had fillers or botulinum toxin in the treatment area in the past 12 months * Subjects who have had treatments with poly-L-lactic acid in the face at any time * Subjects who have had any kind of facial dermabrasion, chemical peel, laser, or IPL treatment including superficial treatments for aesthetic reasons in the past 6 months or for the duration of the study * Subjects who does not agree to avoid using tanning beds or intensive exposure to the sun 2 two weeks prior to each office visit. * Subjects who have any dermatologic conditions including acne, rosacea, eczema, psoriasis, actinic keratosis, severe sun damage, infection or scars within the treatment area * Subjects who have an active inflammatory process (skin eruptions such as cysts, pimples, rashes or hives) or infection within the treatment area * Subjects who have any known cancer including skin cancers (basal cell carcinoma, squamous cell carcinoma and melanoma) * Subjects who have had systemic corticosteroid therapy in the past 6 months or for the duration of the study * Subjects with a known history of poor wound healing * Subjects with a known history of keloids (excessive scarring) * Subjects who are HIV positive * Subjects who have an existing medical condition that the Investigator considers may put the subject at risk or compromise their participation in the study * Subjects who have participated in another research study in the past 30 days * Subjects who are currently involved in any injury litigation claims